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Bioss mt1

Expression of <t>MT1</t> and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

Mt1, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 38 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mt1/product/Bioss
Average 94 stars, based on 38 article reviews

mt1 - by Bioz Stars, 2026-03

94/100 stars

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1) Product Images from "Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders"

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

Journal: The Journal of Headache and Pain

doi: 10.1186/s10194-025-02215-9

Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

Figure Legend Snippet: Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

Techniques Used: Expressing, Comparison

MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

Figure Legend Snippet: MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

Techniques Used: Staining, Expressing

Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

Figure Legend Snippet: Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

Techniques Used: Immunohistochemistry, Fluorescence, Staining

Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

Figure Legend Snippet: Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

Techniques Used:

MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

Figure Legend Snippet: MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

Techniques Used: Expressing, Staining

Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

Figure Legend Snippet: Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

Techniques Used: Immunohistochemistry, Expressing, Staining

Image Search Results

Journal: The Journal of Headache and Pain

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

doi: 10.1186/s10194-025-02215-9

Figure Lengend Snippet: Expression of MT1 and MT2 genes in rat TG, SPG and hypothalamus. ( A ) Comparison of MT1 and MT2 mRNA levels in the TG of male and female rats shows that MT1 expression is significantly higher than MT2. ( B ) In both the hypothalamus (HT) and SPG of male rats, MT1 mRNA levels are also significantly higher than MT2. Data are presented as mean ± SEM, statistical significance indicate as *** p < 0.001, ** p < 0.01, * p < 0.05, and n = 6

Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

Techniques: Expressing, Comparison

Journal: The Journal of Headache and Pain

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

doi: 10.1186/s10194-025-02215-9

Figure Lengend Snippet: MT1 and MT2 immunoreactivity in TG. ( A ) positive MT1 immunoreactivity was observed in the cytoplasm and nuclei of TG neurons (thick arrows) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was observed predominantly in the cytoplasm of neurons (thick arrows), in some cases in their nuclei (thick arrows), and in Aδ-fibers (thin arrows). Negative cells are indicated by asterisks in both ( A ) and ( B ). Blue color represents nuclei staining with DAPI. ( C ) Bar graphs show the number of MT1 and MT2 immunoreactive TG neurons in male and female rats. There was no significant difference in MT1 or MT2 protein expression between sexes. However, the number of MT1-immunoreactive cells was approximately twofold higher than that of MT2 in both males and females. Data are presented as the mean ± SEM, n = 6 and * p < 0.05

Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

Techniques: Staining, Expressing

Journal: The Journal of Headache and Pain

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

doi: 10.1186/s10194-025-02215-9

Figure Lengend Snippet: Double immunohistochemistry of MT1 with CGRP or RAMP1 in TG. ( A ) CGRP (red fluorescence) was expressed in the cytoplasm of TG neurons (thick arrow) and in C- fibers (arrowhead). ( B ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( C ) The merged image shows that MT1 was co-localized with CGRP in the cytoplasm of small to medium-sized neurons (yellow, thick arrow). ( D ) RAMP1 (red fluorescence) was expressed in the cytoplasm of medium to large- sized TG neurons (thick arrow) and in Aδ-fibers (arrowhead). ( E ) MT1 (green fluorescence) was expressed in both cytoplasm and nuclei of TG neurons (thick arrow). ( F ) Their co-localization (yellow) is seen in the merged image. MT1 was co-localized with RAMP1 in the cytoplasm of medium to large -sized neurons (thick arrow). Blue represents nuclei staining with DAPI

Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

Techniques: Immunohistochemistry, Fluorescence, Staining

Journal: The Journal of Headache and Pain

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

doi: 10.1186/s10194-025-02215-9

Figure Lengend Snippet: Localization of MT1 immunoreactivity in the SPG and its co-localization with VIP and PACAP. ( A , D and G ) MT1 immunoreactivity (green) was observed in both the cytoplasm and nuclei of SPG neurons (thick arrows), as well as in SGCs (arrowheads). ( B and E ) VIP immunoreactivity (red) was detected in the cytoplasm of SPG neurons (thick arrows) and in a few C-fibers (arrowhead). ( C and F ) MT1 was co-localized with VIP in the cytoplasm of some SPG neurons (yellow-orange, thick arrows). D , E and F are higher-magnification views of images A , B and C , respectively. ( H ) PACAP immunoreactivity (red) was found in both the cytoplasm and nuclei of some SPG neurons (thick arrow). ( I ) MT1 was co-localized with PACAP in SPG neurons as shown in merged images (yellow/orange, thick arrow)

Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

Techniques:

Journal: The Journal of Headache and Pain

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

doi: 10.1186/s10194-025-02215-9

Figure Lengend Snippet: MT1 and MT2 immunoreactivity in the DRG. ( A ) MT1 expression in DRG was observed in both the cytoplasm and nuclei of neurons (thick arrow) and in SGCs (arrowheads). ( B ) MT2 immunoreactivity was localized in the cytoplasm of neurons and in some cases in their nuclei (thick arrow), and in the Aδ-fibers (thin arrows). The blue color represents nuclei staining with DAPI

Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

Techniques: Expressing, Staining

Journal: The Journal of Headache and Pain

Article Title: Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders

doi: 10.1186/s10194-025-02215-9

Figure Lengend Snippet: Immunohistochemistry of MT1 expression in the wall of cerebral arteries. ( A and B ) MT1 immunoreactivity (red) was observed in all layers of the basilar artery (thick arrows), i.e., in the adventitia layer and the endothelium as well as in the smooth muscle cells. Green represents the internal elastic lamina, autofluorescence (arrowhead in B ) and blue represents nuclei staining with DAPI

Article Snippet: MT1 (bs-0027 R) , 1:200 , Rabbit , Bioss Inc, Woburn, USA , AB_10856893.

Techniques: Immunohistochemistry, Expressing, Staining

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1) Product Images from "Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders"

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